Description

PI 3065 is a potent and selective PI 3-kinase p110δ inhibitor (IC50 = 5 nM; Ki = 1.5 nM). Exhibits >100-fold selectivity over p100α, p100γ and p100β isoforms (IC50 values are 600, 910, >10,000 nM, respectively). Attenuates 4TI tumor growth and metastasis in vivo.

For research use only. We do not sell to patients.

Specification

Chemical Name	6-[[4-(Cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-1H-indol-4-yl)-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine
Purity	≥98%
M.Wt	506.64
Formula	C27H31FN6OS
Solubility	Soluble to 20 mM in DMSO
Storage	Store at -20°C
CAS No.	955977-50-1

PI-3065